Program October 9
09:00 | Cheminformatics & Chemical Systems Biology (Chairs: Rathnam Chaguturu, Petr Bartunek) |
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09:00 | Jordi Mestres Threads and Opportunities of Distant Polypharmacology in Chemical Probes |
09:30 | Tudor Oprea Drugs, Targets, Diseases and the Druggable Proteome |
10:00 | Prudence Mutowo A drug target slim: Using the ChEMBL protein target information and Gene Ontology to navigate protein-ligand target space |
10:20 | Special Topic: Quality of Chemical Probes |
10:20 | Albert A. Antolin Probing cancer genomes: Limitations of currently available chemical tools for effective target validation in cancer |
10:40 | Jonathan Baell The Chemical Probes Portal |
11:00 | Coffee Break |
11:30 | Molecular Imaging (Chairs: Richard Wombacher, Evan Miller) |
11:30 | Carsten Schultz Imaging molecules relevant to disease |
12:00 | Venkata PK Kondapi New near-infrared fluorescent hexose probes for optical imaging of breast cancer |
12:20 | Toru Komatsu Synthetic reconstitution of phagocytosis by chemically induced modification of cell-cell interaction |
12:40 | Péter Kele Double-Clicking bioorthogonally applicable fluorogenic labels |
13:00 | Lunch |
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In parallel | ACS Publications Meet the Editors of ACS Central Science: Carolyn Bertozzi and David Tirrell |
14:00 | Probing the structure and function of PTMs (Chairs: Kjetil Taskén, Christian Ottmann) |
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14:00 | Hilal Lashuel Chemical Biology of Alpha-Synuclein: From novel tools to disease mechanisms to novel Parkinson’s disease therapies |
14:30 | Carlo Unverzagt Convergent Synthesis of Libraries of N-Glycoproteins |
15:00 | Dorothea Fiedler The inositol polyphosphates intersect with protein signaling and metabolic networks via two distinct mechanisms |
15:20 | Yaowen Wu Mechanistic studies of Legionella effector RavZ function in host autophagy using semi-synthetic LC3 proteins |
15:40 | Satpal Virdee Engineered Protein-based Probes for Activity-Based Profiling of the Ubiquitin Conjugation Machinery |
16:00 | Coffee Break |
16:30 | Keynote by Jason Chin Reprogramming the Genetic Code (Chair: Edward Lemke) |
17:15 | Poster Prizes and Farewell Phil Gribbon & Mel Reichman |